A 43-year-old man with advanced HIV (CD4 count of 22 cells/mm3) and metastatic colon cancer developed a scaly rash on his back and shoulders. He is receiving hospice care at a nursing home. He was initially treated with antifungal cream and topical corticosteroids, without any improvement of the rash. A skin smear shows numerous scabies mites and eggs. A diagnosis of crusted scabies is made.
Which one of the following is a recommended treatment for crusted scabies?

Figure 1. Crusted Scabies
This photograph show an erythematous, hyperkeratotic plaques on the shoulder and back of arm.
Photograph from David H. Spach, MD

Figure 2. Scabies:Micro_Edit
Microscope image (magnification x 1100) showing a single Sarcoptes scabiei mite in center, with multiple oval eggs on right and below of the mite.
Photograph from David H. Spach, MD and Thomas Fritsche, MD, PhD
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Question Last Updated
February 4th, 2025
February 4th, 2025
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