A 30-year-old nurse working in a sexual health clinic is evaluated after he experienced a needlestick injury when drawing blood from a patient in the clinic. The nurse immediately and thoroughly washed the wound with soap and water. The source individual undergoes testing with the following results: HIV-1/2 antigen-antibody immunoassay negative, hepatitis B surface antigen (HBsAg) positive, and HCV RNA positive.
For the nurse, what should be done regarding postexposure prophylaxis for hepatitis C virus (HCV) infection?
Figure 1. Testing of Source Patients after Potential Exposure of Health Care Personnel to Hepatitis C Virus, CDC Guidance, United States, 2020*
*Testing of the source patient should be performed as soon as possible (preferably within 48 hours) after exposure.
Abbreviations: NAT = nucleic acid test; HCP = health care personnel
Abbreviations: NAT = nucleic acid test; HCP = health care personnel
Source: Moorman AC, de Perio MA, Goldschmidt R, et al. Testing and Clinical Management of Health Care Personnel Potentially Exposed to Hepatitis C Virus - CDC Guidance, United States, 2020. MMWR Recomm Rep. 2020;69:1-8.
Figure 2. Testing of Health Care Personnel after Potential Exposure to Hepatitis C Virus, CDC Guidance, United States, 2020
*Baseline testing of health care personnel for anti-HCV with reflex to a NAT for HCV RNA if positive should be done as soon as possible (preferably within 48 hours) after the exposure and may be simultaneous with source-patient testing.
Abbreviations: NAT = nucleic acid test; HCP = health care personnel
Abbreviations: NAT = nucleic acid test; HCP = health care personnel
Source: Moorman AC, de Perio MA, Goldschmidt R, et al. Testing and Clinical Management of Health Care Personnel Potentially Exposed to Hepatitis C Virus - CDC Guidance, United States, 2020. MMWR Recomm Rep. 2020;69:1-8.
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Question Last Updated
February 4th, 2025
February 4th, 2025
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