A 27-year-old man is referred to a sexual health clinic for further evaluation of genital ulcers and left-sided inguinal adenopathy. He has just returned from a two-week trip to the Caribbean. While in the Caribbean, he had condomless sex with several women.
On physical examination of the genital region, which one of the following findings would be most consistent with a diagnosis of chancroid?

Figure 1. Ulcerated Penile Lesions
This photograph of a man with chancroid shows three shallow ulcerated lesions that each have an erythematous base and a well-defined border. These lesions are typically painful.
Source: Centers for Disease Control and Prevention Public Health Image Library (Dr. Pirozzi, 1972).

Figure 2. Ulcerated Penile Lesions and Regional Lymphadenopathy
This photograph of a man with chancroid shows two penile ulcerations (blue arrows) and right-sided tense, inguinal adenopathy (black arrow).
Source: Centers for Disease Control and Prevention Public Health Image Library (J Pledger, 1976).

Figure 3. Inguinal Lymphadenopathy with Rupture
This photograph of a woman with chancroid shows marked left-sided inguinal adenopathy, often referred to as a bubo. In this woman, the bubo had ruptured through her overlying inguinal skin (black arrow).
Source: Centers for Disease Control and Prevention Public Health Image Library (Dr. Greg Hammond and Susan Lindsley, 1976).
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Question Last Updated
March 10th, 2025
March 10th, 2025
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