A 61-year-old man with a history of liver transplantation, heart failure, poorly controlled diabetes mellitus, and recent hip fracture presents from his nursing home with a rash. He was living independently until 6 weeks ago, when he fell and fractured his hip. He had a prolonged period of post-operative immobility, but is now starting to ambulate. About 3 weeks earlier, he had a pruritic rash on his groin and shoulders. One week ago, he began developing a thick, crusting rash on the scrotum and penis. Despite treatment with topical steroids, his rash worsened. Examination in the clinic is notable for a crusted, scaling rash in the groin; a diagnosis of crusted scabies is strongly suspected.
Which one of the following is most often identified as a contributor to the development of crusted scabies?

Figure 1. Crusted Scabies in Genital Region
This 71-year-old man with cirrhosis developed an erythematous and scaly rash with marked hyperkeratosis. Microscopic examination showed abundant mites.
Source: Elosua-González M, García-Zamora E. Crusted scabies. N Engl J Med 2017;377:476.
Reproduced with permission. Massachusetts Medical Society. ©2017.
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Question Last Updated
February 4th, 2025
February 4th, 2025
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