A 23-year-old woman is seen by her primary medical care provider for a routine visit. She has no active symptoms and no known medical problems other than mild eczema. She is not taking any medications. During the visit, the medical provider suggests ordering a routine HIV screening test.
Based on Centers for Disease Control and Prevention (CDC) recommendations, which one of the following tests is recommended as the initial HIV screening test?

Figure 1. Centers for Disease Control and Prevention and Association of Public Health Recommended HIV Testing Algorithm
This graphic shows the HIV testing algorithm as recommended in 2014 (and updated in 2018) by the Centers for Disease Control and Prevention and Association of Public Health Laboratories.
NAT = Nucleic Acid Testing
NAT = Nucleic Acid Testing
Source:
(1) Centers for Disease Control and Prevention and Association of Public Health Laboratories. Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations. Published June 27, 2014.
(2) Centers for Disease Control and Prevention and Association of Public Health Laboratories. 2018 Quick reference guide: Recommended laboratory HIV testing algorithm for serum or plasma specimens. Published January 27, 2018.
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Question Last Updated
February 4th, 2025
February 4th, 2025
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