A 13-year-old girl presents with her mother for a routine adolescent medical visit. She has no medical problems, and a confidential history (taken with the mother out of the room) reveals that she has yet to become sexually active. During discussion with the girl and her mother, the mother expresses interest in her daughter receiving the human papillomavirus (HPV) vaccine.
Which one of the following most accurately describes the 9-valent vaccine (9vHPV)?
Figure 1. Human Papillomavirus Vaccine Production
Conceptual rendition of production of human papillomavirus vaccine. The vaccine process involves recombinant synthesis of major capsid L1 proteins that self-assemble as a shell of 72 pentameric capsomeres to form viral-like particles (VLPs). The assembled pseudovirus is very similar to the native human papillomavirus and is highly immunogenic.
Illustration by David H. Spach, MD
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Question Last Updated
February 4th, 2025
February 4th, 2025
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