Table 1. 2021 STI Treatment Guidelines: Diseases Characterized by Genital, Anal, or Perianal UlcersLymphogranuloma Venereum
Recommended
for Lymphogranuloma Venereum
Doxycycline100 mg orally twice daily for 21 days
Doxycycline
Tradename:Doryx, Vibramycin
Alternative
for Lymphogranuloma Venereum
Azithromycin1 g orally once weekly for 3 weeks*
Azithromycin
Tradename:Zithromax*Because this regimen has not been validated, a test-of-cure with C. trachomatis NAAT 4 weeks after completion of treatment can be considered.
Alternative
for Lymphogranuloma Venereum
Erythromycin base500 mg orally four times a day for 21 days
Erythromycin base
Tradename:ErycSource: Workowski KA, Bachmann LH, Chan PA, et al. Sexually transmitted infections treatment guidelines, 2021. Diseases characterized by genital, anal, or perianal ulcers: lymphogranuloma venereum (LGV). MMWR Recomm Rep. 2021;70(No. RR-4):1-187. [2021 STI Treatment Guidelines]