A 28-year-old man is evaluated in a clinic for anal pain and brownish-white rectal discharge that has steadily increased in amount and frequency over the past week. He denies fever, chills, urethral symptoms, bloody stool, genital ulcers or other lesions, and other systemic symptoms. He reports one new male sex partner with whom he engages in receptive anal intercourse, using condoms only intermittently. He is presumptively diagnosed with proctitis.
What are the most common sexually transmitted pathogens that cause proctitis in this situation?

Figure 1. Proctitis
This illustration shows the region of the rectum involved with proctitis (most distal 10 to 12 cm).
Source: Illustration by Jared Travnicek, Cognition Studios
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Question Last Updated
February 4th, 2025
February 4th, 2025
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