A 23-year-old cisgender man who had sex with a cisgender woman 1-week prior is evaluated in a clinic for symptoms of urethral discharge. Physical examination shows evidence of a mucopurulent discharge (Figure 1). A first-void urine leukocyte esterase test is positive, but the clinic does not have the capability for point-of-care staining of urethral secretions. A nucleic acid amplification test (NAAT) is sent for Neisseria gonorrhoeae and Chlamydia trachomatis and the result is pending. He weighs 86 kg.