Abbreviations: Ag/Ab = antigen/antibody combination test; HIV = human immunodeficiency virus; nPEP = nonoccupational postexposure prophylaxis; tenofovir DF = tenofovir disoproxil fumarate.
^a Any positive or indeterminate HIV antibody test should undergo confirmatory testing of HIV infection status.
^b Only if hepatitis C infection was acquired during the original exposure; delayed HIV seroconversion has been seen in persons who simultaneously acquire HIV and hepatitis C infection.
^c If exposed person susceptible to hepatitis B at baseline.
^d If exposed person susceptible to hepatitis C at baseline.
^e If determined to be infected with syphilis and treated, should undergo serologic syphilis testing 6 months after treatment
^f Testing for chlamydia and gonorrhea should be performed using nucleic acid amplification tests. For patients diagnosed with a chlamydia or gonorrhea infection, retesting 3 months after treatment is recommended.
- For men reporting insertive vaginal, anal, or oral sex, a urine specimen should be tested for chlamydia and gonorrhea.
- For women reporting receptive vaginal sex, a vaginal (preferred) or endocervical swab or urine specimen should be tested for chlamydia and gonorrhea.
- For men and women reporting receptive anal sex, a rectal swab specimen should be tested for chlamydia and gonorrhea.
- For men and women reporting receptive oral sex, an oropharyngeal swab should be tested for gonorrhea.
^g If not provided presumptive treatment at baseline, or if symptomatic at follow-up visit.
^h If woman of reproductive age, not using effective contraception, and with vaginal exposure to semen.
ⁱ eCrCl = estimated creatinine clearance calculated by the Cockcroft-Gault formula; eCrClCG = [(140 − age) x ideal body weight] ÷ (serum creatinine x 72) (x 0.85 for females).
^j At first visit where determined to have HIV infection.