A 43-year-old woman with HIV who is taking antiretroviral therapy is seen in clinic for a follow-up visit. Recent laboratory studies showed a CD4 count of 512 cells/mm3 and an undetectable plasma HIV RNA level. At the visit, she is evaluated for vaginal discharge and is diagnosed with trichomoniasis.
Which one of the following is the recommended choice for the treatment of trichomoniasis in this woman with HIV?

Figure 1. Single Dose or 7-Day Course of Metronidazole Treatment of Trichomonas in Women with HIV
In this trial, as shown, higher failure rates occurred with single-dose therapy.
Source: Kissinger P, Mena L, Levison J, et al. A randomized treatment trial: single versus 7-day dose of metronidazole for the treatment of Trichomonas vaginalis among HIV-infected women. J Acquir Immune Defic Syndr. 2010;55:565-71.
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Question Last Updated
March 16th, 2025
March 16th, 2025
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