A 43-year-old woman with chronic HIV is seen in clinic for a follow-up visit. Recent laboratory studies showed a CD4 count of 512 cells/mm3 and an undetectable plasma HIV RNA level. At the visit, she is evaluated for vaginal discharge and is diagnosed with trichomoniasis.
Which one of the following is the recommended choice for treatment of trichomoniasis in this woman with HIV?
Figure 1. Single Dose or 7-Day Course of Metronidazole Treatment of Trichomonas in Women with HIV
In this trial, women with HIV who were diagnosed with trichomoniasis were randomized to receive metronidazole 500 mg orally twice daily for 7 days or metronidazole 2 g orally in a single dose. Higher failure rates occurred with single-dose therapy.
Source: Kissinger P, Mena L, Levison J, et al. A randomized treatment trial: single versus 7-day dose of metronidazole for the treatment of Trichomonas vaginalis among HIV-infected women. J Acquir Immune Defic Syndr. 2010;55:565-71.
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Question Last Updated
February 4th, 2025
February 4th, 2025
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